Active
Lease
Office
Research & Development
Medical

300 W Michigan Ave

300 W Michigan Ave, Ypsilanti, MI 48197

For Lease

Negotiable Modified Gross
Available SF
100 - 10,000 SF
Floor
2
Status
Available
Available
08/04/2026
Sublease
No
Vacant
Yes
DOM
102
Listed
08/04/2026
Updated
11/09/2026
New
300 W Michigan Ave
1 / 1

Overview

300 W. Michigan Avenue is a four-story, 130,000 SF Class B office and lab building in the heart of downtown Ypsilanti, recently renovated to support today's most innovative industries. Built in 1991, the property offers flexible suites — from single offices to 10,000+ SF blocks — configured for corporate office, wet lab, dry lab, and executive use, making it a natural fit for life science, medical device, mobility, robotics, and tech tenants. Amenities include a 160-person auditorium, two passenger elevators, a freight elevator, and a covered parking structure with 369 free spaces. Located within an Opportunity Zone and SMART Zone, the building sits walking distance from downtown Ypsilanti's restaurants, bars, and shops, and less than a mile from I-94 — offering tenants a rare blend of connectivity, character, and cutting-edge infrastructure.

  • Class B office, lab, and hi-tech building in downtown Ypsilanti
  • 130,000 SF across 4 stories, built 1991, recently renovated
  • Suites from 100 SF to 10,000+ SF — flexible and divisible
  • Ideal for life science, medical device, mobility, robotics, and tech tenants
  • Wet lab, dry lab, executive office, and general office space available
  • 160-person auditorium
  • Two (2) passenger elevators + one (1) freight elevator
  • Covered parking structure — 369 free parking spaces
  • Two (2) truck wells / 2-well loading dock
  • Ceiling heights 10'–13'
  • 110/208 2-phase power available; 3-phase available upon request
  • Labs equipped with 60-amp dedicated panel
  • High-speed internet, gas, water, and wastewater infrastructure available
  • Located in an Opportunity Zone and SMART Zone
  • Walking distance to restaurants, bars, and shops
  • Less than 1 mile to I-94
  • Available now — rate negotiable

Spaces & suites

1 Space

Additional Information

City
Ypsilanti
County
Washtenaw
State
MI
Zip Code
48197
Latitude
42.2413557
Longitude
-83.6168147
Secondary Uses
Research & Development
Zoning
C
Zoning Desc.
Center
Building Name
HQe
Building Class
B
Floors
2
Year Built
1991
Parking Spaces
360
Ceiling Height
10' - 13'
Nearest Interstate
1-94 - 1 mi
Nearest Airport
Detroit Metropolitan Wayne County Airport - 16.2 mi
Parcel APN
11-11-40-481-019
Listing ID
612d4278

Parcel & Location