ID 612d4278
300 W Michigan Ave
For Lease
Negotiable Modified Gross- Available SF
- 100 - 10,000 SF
- Floor
- 2
- Status
- Available
- Available
- 08/04/2026
- Sublease
- No
- Vacant
- Yes
- DOM
- 102
- Listed
- 08/04/2026
- Updated
- 11/09/2026

Overview
300 W. Michigan Avenue is a four-story, 130,000 SF Class B office and lab building in the heart of downtown Ypsilanti, recently renovated to support today's most innovative industries. Built in 1991, the property offers flexible suites — from single offices to 10,000+ SF blocks — configured for corporate office, wet lab, dry lab, and executive use, making it a natural fit for life science, medical device, mobility, robotics, and tech tenants. Amenities include a 160-person auditorium, two passenger elevators, a freight elevator, and a covered parking structure with 369 free spaces. Located within an Opportunity Zone and SMART Zone, the building sits walking distance from downtown Ypsilanti's restaurants, bars, and shops, and less than a mile from I-94 — offering tenants a rare blend of connectivity, character, and cutting-edge infrastructure.
- Class B office, lab, and hi-tech building in downtown Ypsilanti
- 130,000 SF across 4 stories, built 1991, recently renovated
- Suites from 100 SF to 10,000+ SF — flexible and divisible
- Ideal for life science, medical device, mobility, robotics, and tech tenants
- Wet lab, dry lab, executive office, and general office space available
- 160-person auditorium
- Two (2) passenger elevators + one (1) freight elevator
- Covered parking structure — 369 free parking spaces
- Two (2) truck wells / 2-well loading dock
- Ceiling heights 10'–13'
- 110/208 2-phase power available; 3-phase available upon request
- Labs equipped with 60-amp dedicated panel
- High-speed internet, gas, water, and wastewater infrastructure available
- Located in an Opportunity Zone and SMART Zone
- Walking distance to restaurants, bars, and shops
- Less than 1 mile to I-94
- Available now — rate negotiable
Spaces & suites
1 SpaceAdditional Information
- City
- Ypsilanti
- County
- Washtenaw
- State
- MI
- Zip Code
- 48197
- Latitude
- 42.2413557
- Longitude
- -83.6168147
- Secondary Uses
- Research & Development
- Zoning
- C
- Zoning Desc.
- Center
- Building Name
- HQe
- Building Class
- B
- Floors
- 2
- Year Built
- 1991
- Parking Spaces
- 360
- Ceiling Height
- 10' - 13'
- Nearest Interstate
- 1-94 - 1 mi
- Nearest Airport
- Detroit Metropolitan Wayne County Airport - 16.2 mi
- Parcel APN
- 11-11-40-481-019
- Listing ID
- 612d4278
- City
- Ypsilanti
- County
- Washtenaw
- State
- MI
- Zip Code
- 48197
- Latitude
- 42.2413557
- Longitude
- -83.6168147
- Secondary Uses
- Research & Development
- Zoning
- C
- Zoning Desc.
- Center
- Building Name
- HQe
- Building Class
- B
- Floors
- 2
- Year Built
- 1991
- Parking Spaces
- 360
- Ceiling Height
- 10' - 13'
- Nearest Interstate
- 1-94 - 1 mi
- Nearest Airport
- Detroit Metropolitan Wayne County Airport - 16.2 mi
- Parcel APN
- 11-11-40-481-019
- Listing ID
- 612d4278
