Active
Lease
Office

Second Floor - Howell Health Hub

645 W Grand River Ave, Howell, MI 48843

For Lease

$20/SF/Year NNN
Space Name
Second Floor
Available SF
36,000 SF
Status
Available
Available
Available now
Sublease
No
Vacant
No
Created
03/11/2026
Updated
03/11/2026

Overview

Howell Health Hub is located at 645 W. Grand River Avenue and is a well-established professional and medical office building near Downtown Howell, Michigan. Spanning 108,231 square feet across three stories, the building sits on 5.33 professionally landscaped acres. Benefit from property features such as an expansive 400-space surface parking lot, recent improvements to the roof and HVAC system, and a full-building backup generator in case of emergencies.

Well-maintained, built-out space from 4,000- to 80,000 square feet is immediately available for occupancy. Office amenities and features include an attended lobby entrance, conference rooms, natural-light-filled private perimeter offices, and primarily open floor plans, allowing for ample space for individual workstations. Situated on the south side of the Grand River at Byron Road, 645 W Grand River Avenue is just west of Michigan Avenue and within walking distance to downtown. Tenants and guests are close to Diamonds Steaks and Seafood, Uptown Coffeehouse, M Street Baking Company, 2FOG’s Pub, the Historic Howell Theater, the Livingston County Courthouse, and more. For convenient travel to and from The 645 Building, use Route 59 and I-96 for easy highway accessibility.

Listing Information

City
Howell
State
MI
Zip Code
48843
Parcel APN
17-35-202-093
Listing ID
34ca582d

Parcel & Location